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Professional area
Accessing the professional area you will discover products and protocols that mesoestetic designs specifically for medical and aesthetic professionals.
A new generation of solutions for the treatment of blemishes caused by acne, acting in a comprehensive manner to restore the quality and natural balance of the skin.
corrects, regulates and prevents
A multi-dimensional action that treats blemishes and improves the overall quality of oily skin.
comprehensive approach
Combines an exclusive professional method and an at-home follow-up routine
adaptable solutions
Designed for the treatment of acne-prone skin as well as oily skins with active blemishes.
proven effectiveness
Studies performed on cell cultures and in real cases have proven its effectiveness.
What is blemiderm®?
blemiderm® is a comprehensive method for treating different levels of severity of acne, by reducing the appearance of blemishes, intensively correcting them and improving the quality of the skin, reducing shine and refining its texture.
"I have friends who took medication to treat acne. I wanted to avoid it, because I know it's a very strong treatment, but after using blemiderm®, I am very happy with my choice. I totally recommend it."
Eric, 18 years old
"Acne made me feel very insecure. After the treatment, I can see that my skin is much smoother, the painful spots have disappeared and I feel much more comfortable with myself.”
Lidia, 18 years old
"I noticed that outbreaks have decreased a lot, both in terms of intensity and in terms of the number of lesions. I would certainly recommend this treatment."
The result of the latest advances in acne research, mesostetic ® has developed blemiderm ® . A new generation of solutions for addressing blemishes caused by acne, acting comprehensively on the different pathways which promote its appearance.
A comprehensive solution based on the latest scientific evidence that treats blemishes and restores the quality of oily skin with active imperfections.
control of the hormonal pathway
5α-reductase pathway (DHT) ¹
IGF-1 pathway, activated by the exposome ²
Selective antimicrobial activity
Selective activity on the pathogenic phylotype of C.acnes ³
Inhibition of inflammation
Stimulated by IGF-1 and C.acnes ⁴
Innovative formulas with proven effectiveness
blemisome complex
A delivery system that has been designed using an exclusive combination of active ingredients that direct its action to target cells.
Inhibition of 5α-reductase gene expression ⁵
Main enzyme responsible for activating hyperseborrea and hyperkeratosis.
Increase in RAR- δ ⁶ expression
Retinoic acid receptor, which enhances skin rejuvenation
Ex-vivo study of biodistribution in skin explants ⁷
High penetration of the delivered active ingredients to the target location through transethosomes.
The blemiderm® medical method includes a medical protocol in the clinic as well as an at-home routine to maximise the results.The treatment lasts for approximately 3 months.
TREATMENT PROGRAMME
total sessions
3 sessions (every 15 days)
treatment duration
3 months
protocol in medical consultation
blemiderm®: Medical treatment
at-home routine
blemiderm®: topical solutions and nutritional supplements
I am a professional and I want to offer treatment in my office
Frequently asked questions about the blemiderm® medical method
Is this treatment completely painless?
Yes. During the professional session, application of the mask may cause itching and stinging - this is an expected effect. It can be controlled by offering the user a fan or an item that allows them to fan themselves to improve tolerability.
Do the blemishes disappear completely?
Blemishes are significantly reduced, and the quality of the skin improves notably. Acne is a chronic condition triggered mainly by a hyperactivation of hormonal pathways. Using an at-home blemiderm® routine for at least 3 months and repeating the professional protocol as per a professional's opinion will help to keep the blemishes under control
When is the best time to use the blemiderm® method?
For optimal results, we recommend that you use the method during periods when your exposure to the sun is low. This protects the skin from the onset of PIH (post-inflammatory hyperpigmentation) while acting when the acne is most prevalent.
When can the results be seen?
The results start to be noticeable after the first session in clinic. After 15 days, a reduction in redness and in the number of active blemishes is noted.
When should the at-home routine begin?
These are carried out at the same time as the professional sessions in the clinic. After the first treatment session, the patient can start using purifying mousse as part of their daily facial hygiene routine. They can then start to apply blemiderm® treatment at night once the skin has recovered its eudermic state, some 24-48 hours later. Prolonging the at-home treatment for 3 months is essential for ensuring that the desired result is achieved.
Can it be combined with other pharmacological acne treatments?
Yes. The blemiderm® method can be used together with other oral and topical treatments such as antibiotics and hormonal therapies. However, the combination with topical or oral retinoids is not recommended as these treatments make the skin very sensitive, which could lead to an over-reaction to the blemiderm® method.
In addition to the products included in the blemiderm® home pack, can other anti-blemish solutions products be used?
Yes. We recommend that you combine the treatment with the probiotic-based blemiderm® caps nutritional supplement. This is a product that uses the latest scientific research relating to the gut-skin axis. Other recommended products: Blemiderm® local control, due to its focussed action on blemishes; exfoliating and matifying pure renewing mask, based on white clay and blemiderm® resurfacing gel, which acts as an intensive skin rejuvenator to prevent blemishes.
1. INF468. UB. Report on the inhibition of sebum production with EGCG and Australian Maclura. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.2. INF463. UB. Informe de la inhibición de la producción de sebo inducida con IGF-1 y tratados con EGCG [Report on the inhibition of sebum production induced with IGF-1 and treated with EGCG]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.3. INF487. UB. Informe de la eficacia antimicrobiana sobre S. epidermidis y C. acnes filotipo IA1 con retinol y Maclura Australiana [Report on the antimicrobial efficacy of retinol and Maclura cochinchinensis on S. epidemis and C. acnes phylotype I]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.4. INF466. UB. Informe efecto antinflamatorio en sebocitos tratados con EGCG y Maclura Australiana [Report on the anti-inflammatory effect on sebocytes treated with EGCG and Maclura cochinchinensis]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.5. INF462. UB. Informe de la vía hormonal en sebocitos tratados con retinol-neem-enoxolona [Report on the hormonal pathway in sebocytes treated with retinol-neem-enoxolone]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022. 6. INF462. UB. Informe de la renovación epidérmica en queratinocitos tratados con retinol y Maclura Australiana [Report on epidermal rejuvenation in keratinocytes treated with retinol and Maclura cochinchinensis]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2023.7. INF487. UB. Informe de estudio de biodistribución de transetosomas para acné en explante cutáneo [Report on the study of the biodistribution of transethosomes for acne using skin explants.] Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.8. INF468. UB. Report on the inhibition of sebum production with EGCG and Australian Maclura. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.9. INF466. UB. Informe efecto antinflamatorio en sebocitos tratados con EGCG y Maclura Australiana [Report on the anti-inflammatory effect on sebocytes treated with EGCG and Maclura cochinchinensis]. Biotechnology Unit. mesoestetic Pharma Group S.L. 2022.
