skinretin 0,3%

visible results after 28 days of use¹

-50%

reduction of wrinkles

+43%

improvement in elasticity

+70%

better skin texture

+80%

more elastic, brighter, firmer and smoother skin

100%

very good tolerability

results before and after

Before

After

Before

After

what is skinretin 0.3%? and its benefits

Spots, expression lines, wrinkles and loss of firmness are the most common manifestations of skin aging.

skinretin 0.3% is an intensive solution that achieves maximum anti-aging efficacy and maintains an optimal balance in terms of skin tolerance

Formula and texture suited to all skin types to combat signs of aging.

main ingredients in skinretin 0.3%

global anti-aging action

A combination that maximises the formula's anti-aging potential and maintains high tolerance levels.

0,3% pure retinol

0,7% bakuchiol

Regenerative and rebalancing action

It enhances regeneration and stimulates the skin microbiota, favouring an optimal barrier function.

post-biotic complex

how to use retinol for the first time

use it at night

Start by applying it on alternate nights. If you have sensitive skin, you can space the applications at the beginning of the treatment.
Apply skinretin 0.3% on clean, dry skin, avoiding the eye contour.

From the second week onwards, tolerance will be good, so you can increase the frequency of applications

during the day

Do not use skinretin 0.3%, apply it only at night, and don't forget to use sunscreen.

Mild dryness, slight irritation and little scaling may occur in the first applications These effects are due to the process of your skin adapting to retinol; they are expected and temporary.

It reinforces the restorative and moisturising action in applications without skinretin 0.3% until your skin has become accustomed to retinol

efficacy endorsed by science

x9,8

cell proliferation²

regenerates

It favours the proliferation of fibroblasts, the cells responsible for collagen and elastin synthesis.

SEE RESULTS AFTER 16HCLOSE RESULTS

99%

epidermal thickness²

renews the skin

Increases the expression of cytokeratin 14, fluorescent green marker, an indicator of optimal skin renewal

See resultsCLOSE RESULTS

FAQ skinretin 0,3%

can I use retinol if I have sensitive skin?

skinretin 0.3% is recommended for all skin types. If your skin is sensitive, in first applications apply a moisturising cream or restorative serum before applying retinol. You can also space the application further at the beginning, leaving a two-night interval in the first week. You will be able to gradually increase the frequency of application.

what should I do if my skin suffers scaling, dryness or irritation?

Mild dryness, slight irritation and little scaling may occur. These effects are due to the process of your skin adapting to retinol; they are expected and temporary. If irritation persists, temporarily suspend the treatment.

is it normal for skin to get irritated in the first applications?

Yes, your skin is being renewed. Boost your daily routine with nourishing and restorative products to smoothen the effects of retinisation, and don't forget to use sunscreen.

at what age can a retinol treatment be initiated?

Products with retinol can be used from adolescence onwards; however, the anti-aging benefits of skinretin 0.3% are indicated for people over 30 years of age with emerging signs of aging.

can I apply retinol on the neck and neckline?

Yes, following the recommended application guidelines and respecting the retinisation process.
You must bear in mind that these are sensitive areas to which you must pay special attention.

if I use a treatment with tranexamic acid, how can I incorporate retinol?

We recommend a progressive retinisation on alternate nights, and once the skin shows good retinol tolerance, we can start incorporating tranexamic acid on nights in which retinol is not applied.

is it advisable to apply a serum before skinretin 0.3%?

You can apply any moisturising or restorative serum, but we recommend applying it on its own. If your skin is sensitive, using a serum beforehand will soften the effects of retinisation.

retinol: what is it and what are its benefits?

Find out more about retinol on our blog, see more here

¹ Medical Affairs Unit. MESO_0822 studies to assess the safety, efficacy and tolerance of the cosmetic product skinretin 0.3%. mesoestetic Pharma Group S.L. 2022

² Biotechnology Unit Wound healing trial on fibroblasts with Retinol + Bakuchiol + Post-biotic complex mesoestetic Pharma Group S.L. 2022

Treatment area	face.
frequency of use	occasional.
time of use	evening.

Product category	home
Age	all
Routine stage	treatment
Type of skin	all
indication	Global anti-ageing night cream. Rejuvenates, brightens and revitalises skin.
Treatment area	face